Endocrine Abstracts

Introduction: Thyroid storm (TS) is a severe manifestation of thyrotoxicosis, (1). It is most commonly seen in Graves’ disease and can occur due to a non-compliance to anti-thyroid medications Management includes both addressing end organ damage and attaining a euthyroid state. We report the case of a patient who presented a thyroid storm complicating a grave’s disease and unmasking, during its management, a corticotropic insufficiency.Clinical...

Introduction: Adrenal insufficiency is rarely diagnosed during pregnancy. In the absence of treatment it is associated with high maternal-foetal morbidity and mortality. We report the case of a twenty-one years old female patient, diagnosed with adrenal insufficiency during a diabetic pregnancy of 12 weeks of gestation.Observation: Twenty-one years old female patient, diagnosed with type 1 diabetes since the age of 15, Referred to our department for the ...

Introduction: Mitochondrial diabetes represents about 1% of diabetes but still very often misunderstood. The most frequent mutation is 3243A >G of the mtDNA, which is responsible for the maternally inherited diabetes and deafness syndrome (MIDD). We report an observation of a patient with strong suspicion of mitochondrial diabetes.Case presentation: 43-year-old female patient, with diabetes for 5 years on an Insulin Therapy.Anamnesis:&hypen;&...

Introduction: Metabolic disorders are a relevant cause of morbidity and disability in patients with Cushing’s syndrome (CS) even after a successful treatment. The aim of our study was to assess the prevalence of metabolic syndrome in our CS patients, as central obesity, dyslipidemia, diabetes, and hypertension, and to discuss the main adverse effects of CS on metabolism and emphasize the importance of long-term monitoring and treatment of these complications.Patients and ...

Introduction: Mild autonomous cortisol secretion (MACS) is a term used to describe biochemical evidence of abnormal cortisol secretion in patients with adrenocortical adenomas (ACA), but without the classical external manifestations of overt Cushing’s syndrome (CS).Materials and Methods: In this study, we report a case of patient who presents mild autonomous cortisol secretion among incidentally discovered adrenal masses; followed in unit of the end...

Introduction: The prevalence of megaloblastic anemia in the adult population is poorly documented, but in the elderly, it has been clearly shown that the prevalence of macrocytic anemia increases after the age of 65 years especially in men. The most frequent etiology of vitamin B12 and folate deficiency is malabsorption. They have an action in the conversion of homocysteine to methionine: an increase in homocysteinaemia is currently considered a cardiovascular risk factor. Str...

Introduction: – The "super bone scan" is a peculiar condition characterized by extremely high bone uptake compared to soft tissue, with no visualization of renal radioactivity.– Super bone scan has been described in relation to several conditions such as metastatic disease (prostate/breast cancer), metabolic bone disease (Paget’s disease/hyperparathyroidism) and myeloproliferative disorders.Clinical Case: – A 75 year old man, ...

Introduction: Cataracts are an opacification of the crystalline lens, either partial or total, primarily caused by senescence, and rarely of metabolic origin. We present the case of a 24-year-old newly diagnosed with bilateral cataracts.Case Presentation: E.S., a 24-year-old with newly discovered diabetes on insulin therapy, presented with a sudden and significant decrease in visual acuity. Ophthalmologic examination revealed bilateral cataracts with an ...

Introduction: Dupuytren’s disease (DD) corresponds to a chronic palpable thickening of the palmar aponeurosis which leads to different degrees of irreducible flexion of the fingers. It is one of the manifestations of hand syndrome in diabetes mellitus. We highlight through this report the occurrence of DD as a manifestation of diabetic hand syndrome in a patient with type 2 diabetes mellitus.Observation: A sixty-six year old patient, truck driver, t...

Introduction: Mauriac syndrome (MS) is a rare complication of type 1 diabetes mellitus (DM1), characterized by hepatomegaly (hepatic glycogenosis), puberty and growth delay, transaminase elevation and reduction of IGF1 (insulin-like growth factor 1). MS is more common in children and adolescents with poor glycemic control.Case Report: A 17-years-old Type 1 diabetic boy was admitted for evaluation of growth retardation. He was diagnosed to have T1DM 15 ye...